HIF-1α Inhibition Reduces Nasal Inflammation in a Murine Allergic Rhinitis Model

BACKGROUND: Hypoxia-inducible factor 1α (HIF-1α) is an important regulator of immune and inflammatory responses. We hypothesized that nasal allergic inflammation is attenuated by HIF-1α inhibition and strengthened by HIF-1α stabilization. OBJECTIVE: To elucidate the role of HIF-1α in a murine model...

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Detalles Bibliográficos
Autores principales: Zhou, Han, Chen, Xi, Zhang, Wei-Ming, Zhu, Lu-Ping, Cheng, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486851/
https://www.ncbi.nlm.nih.gov/pubmed/23133644
http://dx.doi.org/10.1371/journal.pone.0048618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486851/
https://www.ncbi.nlm.nih.gov/pubmed/23133644
http://dx.doi.org/10.1371/journal.pone.0048618

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