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Trps1 and Its Target Gene Sox9 Regulate Epithelial Proliferation in the Developing Hair Follicle and Are Associated with Hypertrichosis

Hereditary hypertrichoses are a group of hair overgrowth syndromes that are extremely rare in humans. We have previously demonstrated that a position effect on TRPS1 is associated with hypertrichosis in humans and mice. To gain insight into the functional role of Trps1, we analyzed the late morphoge...

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Detalles Bibliográficos
Autores principales: Fantauzzo, Katherine A., Kurban, Mazen, Levy, Brynn, Christiano, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486859/
https://www.ncbi.nlm.nih.gov/pubmed/23133399
http://dx.doi.org/10.1371/journal.pgen.1003002