Impact of Stoichiometry Representation on Simulation of Genotype-Phenotype Relationships in Metabolic Networks

Genome-scale metabolic networks provide a comprehensive structural framework for modeling genotype-phenotype relationships through flux simulations. The solution space for the metabolic flux state of the cell is typically very large and optimization-based approaches are often necessary for predictin...

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Detalles Bibliográficos
Autores principales: Brochado, Ana Rita, Andrejev, Sergej, Maranas, Costas D., Patil, Kiran R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486866/
https://www.ncbi.nlm.nih.gov/pubmed/23133362
http://dx.doi.org/10.1371/journal.pcbi.1002758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486866/
https://www.ncbi.nlm.nih.gov/pubmed/23133362
http://dx.doi.org/10.1371/journal.pcbi.1002758

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