Histone H1 Plays a Role in Heterochromatin Formation and VSG Expression Site Silencing in Trypanosoma brucei

The African sleeping sickness parasite Trypanosoma brucei evades the host immune system through antigenic variation of its variant surface glycoprotein (VSG) coat. Although the T. brucei genome contains ∼1500 VSGs, only one VSG is expressed at a time from one of about 15 subtelomeric VSG expression...

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Detalles Bibliográficos
Autores principales: Povelones, Megan L., Gluenz, Eva, Dembek, Marcin, Gull, Keith, Rudenko, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486875/
https://www.ncbi.nlm.nih.gov/pubmed/23133390
http://dx.doi.org/10.1371/journal.ppat.1003010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486875/
https://www.ncbi.nlm.nih.gov/pubmed/23133390
http://dx.doi.org/10.1371/journal.ppat.1003010

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