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Identification of a Novel Splice Variant Form of the Influenza A Virus M2 Ion Channel with an Antigenically Distinct Ectodomain

Segment 7 of influenza A virus produces up to four mRNAs. Unspliced transcripts encode M1, spliced mRNA2 encodes the M2 ion channel, while protein products from spliced mRNAs 3 and 4 have not previously been identified. The M2 protein plays important roles in virus entry and assembly, and is a targe...

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Detalles Bibliográficos
Autores principales: Wise, Helen M., Hutchinson, Edward C., Jagger, Brett W., Stuart, Amanda D., Kang, Zi H., Robb, Nicole, Schwartzman, Louis M., Kash, John C., Fodor, Ervin, Firth, Andrew E., Gog, Julia R., Taubenberger, Jeffery K., Digard, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486900/
https://www.ncbi.nlm.nih.gov/pubmed/23133386
http://dx.doi.org/10.1371/journal.ppat.1002998