Ubiquitin-Based Probes Prepared by Total Synthesis To Profile the Activity of Deubiquitinating Enzymes

Epitope-tagged active-site-directed probes are widely used to visualize the activity of deubiquitinases (DUBs) in cell extracts, to investigate the specificity and potency of small-molecule DUB inhibitors, and to isolate and identify DUBs by mass spectrometry. With DUBs arising as novel potential dr...

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Detalles Bibliográficos
Autores principales: de Jong, Annemieke, Merkx, Remco, Berlin, Ilana, Rodenko, Boris, Wijdeven, Ruud H M, El Atmioui, Dris, Yalçin, Zeliha, Robson, Craig N, Neefjes, Jacques J, Ovaa, Huib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487179/
https://www.ncbi.nlm.nih.gov/pubmed/23011887
http://dx.doi.org/10.1002/cbic.201200497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487179/
https://www.ncbi.nlm.nih.gov/pubmed/23011887
http://dx.doi.org/10.1002/cbic.201200497

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