SOX2 haploinsufficiency is associated with slow progressing hypothalamo-pituitary tumours

SOX2 is an early developmental transcription factor and marker of stem cells that has recently been implicated in the development of the pituitary gland. Heterozygous SOX2 mutations have been described in patients with hypopituitarism and severe ocular abnormalities. In the majority of published cas...

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Detalles Bibliográficos
Autores principales: Alatzoglou, Kyriaki S, Andoniadou, Cynthia L, Kelberman, Daniel, Buchanan, Charles R, Crolla, John, Arriazu, Maria Cristina, Roubicek, Martin, Moncet, Daniel, Martinez-Barbera, Juan P, Dattani, Mehul T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487182/
https://www.ncbi.nlm.nih.gov/pubmed/21919124
http://dx.doi.org/10.1002/humu.21606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487182/
https://www.ncbi.nlm.nih.gov/pubmed/21919124
http://dx.doi.org/10.1002/humu.21606

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