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Pharmacogenetics of Efficacy and Safety of HCV Treatment in HCV-HIV Coinfected Patients: Significant Associations with IL28B and SOCS3 Gene Variants

BACKGROUND AND AIMS: This was a safety and efficacy pharmacogenetic study of a previously performed randomized trial which compared the effectiveness of treatment of hepatitis C virus infection with pegylated interferon alpha (pegIFNα) 2a vs. 2b, both with ribavirin, for 48 weeks, in HCV-HIV coinfec...

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Detalles Bibliográficos
Autores principales: Vidal, Francesc, López-Dupla, Miguel, Laguno, Montserrat, Veloso, Sergi, Mallolas, Josep, Murillas, Javier, Cifuentes, Carmen, Gallart, Lluis, Auguet, Teresa, Sampériz, Gloria, Payeras, Antoni, Hernandez, Pilar, Arnedo, Mireia, Gatell, Josep Ma, Richart, Cristóbal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487790/
https://www.ncbi.nlm.nih.gov/pubmed/23133602
http://dx.doi.org/10.1371/journal.pone.0047725