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A gene-protein assay for human epidermal growth factor receptor 2 (HER2): brightfield tricolor visualization of HER2 protein, the HER2 gene, and chromosome 17 centromere (CEN17) in formalin-fixed, paraffin-embedded breast cancer tissue sections

BACKGROUND: The eligibility of breast cancer patients for human epidermal growth factor receptor 2 (HER2)-directed therapies is determined by the HER2 gene amplification and/or HER2 protein overexpression status of the breast tumor as determined by in situ hybridization (ISH) or immunohistochemistry...

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Detalles Bibliográficos
Autores principales: Nitta, Hiroaki, Kelly, Brian D, Padilla, Mary, Wick, Nikolaus, Brunhoeber, Patrick, Bai, Isaac, Singh, Shalini, Ranger-Moore, Jim, Bieniarz, Chris, Tsuda, Hitoshi, Grogan, Thomas M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487810/
https://www.ncbi.nlm.nih.gov/pubmed/22647525
http://dx.doi.org/10.1186/1746-1596-7-60