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Asymmetric Divergence in Structure and Function of HCN Channel Duplicates in Ciona intestinalis

Hyperpolarization-activated Cyclic Nucleotide (HCN) channels are voltage-gated cation channels and are critical for regulation of membrane potential in electrically active cells. To understand the evolution of these channels at the molecular level, we cloned and examined two of three HCN homologs of...

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Detalles Bibliográficos
Autores principales: Jackson, Heather A., Hegle, Andrew, Nazzari, Hamed, Jegla, Timothy, Accili, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487815/
https://www.ncbi.nlm.nih.gov/pubmed/23133599
http://dx.doi.org/10.1371/journal.pone.0047590