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Impact of Salinomycin on human cholangiocarcinoma: induction of apoptosis and impairment of tumor cell proliferation in vitro

BACKGROUND: Cholangiocarcinoma (CC) is a primary liver cancer with increasing incidence worldwide. Despite all efforts made in past years, prognosis remains to be poor. At least in part, this might be explained by a pronounced resistance of CC cells to undergo apoptosis. Thus, new therapeutic strate...

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Detalles Bibliográficos
Autores principales: Lieke, Thorsten, Ramackers, Wolf, Bergmann, Sabine, Klempnauer, Jürgen, Winkler, Michael, Klose, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487825/
https://www.ncbi.nlm.nih.gov/pubmed/23057720
http://dx.doi.org/10.1186/1471-2407-12-466