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Enhanced vesicular stomatitis virus (VSVΔ51) targeting of head and neck cancer in combination with radiation therapy or ZD6126 vascular disrupting agent

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is the 5th most common cancer worldwide. Locally advanced HNSCC are treated with either radiation or chemo-radiotherapy, but still associated with high mortality rate, underscoring the need to develop novel therapies. Oncolytic viruses have b...

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Detalles Bibliográficos
Autores principales: Alajez, Nehad M, Mocanu, Joseph D, Krushel, Tiffany, Bell, John C, Liu, Fei-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487860/
https://www.ncbi.nlm.nih.gov/pubmed/22704542
http://dx.doi.org/10.1186/1475-2867-12-27