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Deacetylation of H4-K16Ac and heterochromatin assembly in senescence

BACKGROUND: Cellular senescence is a stress response of mammalian cells leading to a durable arrest of cell proliferation that has been implicated in tumor suppression, wound healing, and aging. The proliferative arrest is mediated by transcriptional repression of genes essential for cell division b...

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Detalles Bibliográficos
Autores principales: Contrepois, Kévin, Thuret, Jean-Yves, Courbeyrette, Régis, Fenaille, François, Mann, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487866/
https://www.ncbi.nlm.nih.gov/pubmed/22932127
http://dx.doi.org/10.1186/1756-8935-5-15