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Deacetylation of H4-K16Ac and heterochromatin assembly in senescence
BACKGROUND: Cellular senescence is a stress response of mammalian cells leading to a durable arrest of cell proliferation that has been implicated in tumor suppression, wound healing, and aging. The proliferative arrest is mediated by transcriptional repression of genes essential for cell division b...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487866/ https://www.ncbi.nlm.nih.gov/pubmed/22932127 http://dx.doi.org/10.1186/1756-8935-5-15 |