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The Pentameric Channel of COMPcc in Complex with Different Fatty Acids

BACKGROUND: COMPcc forms a pentameric left-handed coiled coil that is known to bind hydrophilic signaling molecules such as vitamin D(3), and vitamin A. PRINCIPAL FINDINGS: In an integrated approach we reveal the unique binding properties of COMPcc for saturated and unsaturated fatty acids. Our obse...

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Detalles Bibliográficos
Autores principales: MacFarlane, Ainsley A., Orriss, George, Okun, Natalie, Meier, Markus, Klonisch, Thomas, Khajehpour, Mazdak, Stetefeld, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487892/
https://www.ncbi.nlm.nih.gov/pubmed/23133613
http://dx.doi.org/10.1371/journal.pone.0048130