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Silencing Prion Protein in MDA-MB-435 Breast Cancer Cells Leads to Pleiotropic Cellular Responses to Cytotoxic Stimuli

Prion protein (PrP) is well studied for its pathogenic role in prion disease, but its potential contribution to other pathological processes is less understood. PrP is expressed in a variety of cancers and at least in pancreatic and breast cancers, its expression appears to be associated with poor p...

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Detalles Bibliográficos
Autores principales: Yu, Guohua, Jiang, Liming, Xu, Yuanyuan, Guo, Hongwei, Liu, Huiyan, Zhang, Yi, Yang, Huaiyi, Yuan, Chonggang, Ma, Jiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487893/
https://www.ncbi.nlm.nih.gov/pubmed/23133614
http://dx.doi.org/10.1371/journal.pone.0048146