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High-throughput comparison of gene fitness among related bacteria

BACKGROUND: The contribution of a gene to the fitness of a bacterium can be assayed by whether and to what degree the bacterium tolerates transposon insertions in that gene. We use this fact to compare the fitness of syntenic homologous genes among related Salmonella strains and thereby reveal diffe...

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Detalles Bibliográficos
Autores principales: Canals, Rocio, Xia, Xiao-Qin, Fronick, Catrina, Clifton, Sandra W, Ahmer, Brian MM, Andrews-Polymenis, Helene L, Porwollik, Steffen, McClelland, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487940/
https://www.ncbi.nlm.nih.gov/pubmed/22646920
http://dx.doi.org/10.1186/1471-2164-13-212