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Assessment of T-dependent and T-independent immune responses in cattle using a B cell ELISPOT assay

Understanding the mechanisms that maintain protective antibody levels after immunisation is important for vaccine design. In this study, we have determined the kinetics of plasma and memory B cells detectable in the blood of cattle immunised with model T-dependent or T-independent antigens. Immunisa...

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Detalles Bibliográficos
Autores principales: Grant, Clare FJ, Lefevre, Eric A, Carr, B Veronica, Prentice, Helen, Gubbins, Simon, Pollard, Andrew J, Charreyre, Catherine, Charleston, Bryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487944/
https://www.ncbi.nlm.nih.gov/pubmed/23050495
http://dx.doi.org/10.1186/1297-9716-43-68