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Assessment of T-dependent and T-independent immune responses in cattle using a B cell ELISPOT assay
Understanding the mechanisms that maintain protective antibody levels after immunisation is important for vaccine design. In this study, we have determined the kinetics of plasma and memory B cells detectable in the blood of cattle immunised with model T-dependent or T-independent antigens. Immunisa...
Autores principales: | Grant, Clare FJ, Lefevre, Eric A, Carr, B Veronica, Prentice, Helen, Gubbins, Simon, Pollard, Andrew J, Charreyre, Catherine, Charleston, Bryan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487944/ https://www.ncbi.nlm.nih.gov/pubmed/23050495 http://dx.doi.org/10.1186/1297-9716-43-68 |
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