Increasing extracellular matrix collagen level and MMP activity induces cyst development in polycystic kidney disease

BACKGROUND: Polycystic Kidney Disease (PKD) kidneys exhibit increased extracellular matrix (ECM) collagen expression and metalloproteinases (MMPs) activity. We investigated the role of these increases on cystic disease progression in PKD kidneys. METHODS: We examined the role of type I collagen (col...

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Detalles Bibliográficos
Autores principales: Liu, Bin, Li, Chenghai, Liu, Zijuan, Dai, Zonghan, Tao, Yunxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487993/
https://www.ncbi.nlm.nih.gov/pubmed/22963260
http://dx.doi.org/10.1186/1471-2369-13-109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487993/
https://www.ncbi.nlm.nih.gov/pubmed/22963260
http://dx.doi.org/10.1186/1471-2369-13-109

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