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Valproic acid decreases urothelial cancer cell proliferation and induces thrombospondin-1 expression
BACKGROUND: Prevention of bladder cancer recurrence is a central challenge in the management of this highly prevalent disease. The histone deacetylase inhibitor valproic acid (sodium valproate) has anti-angiogenic properties and has been shown to decrease bladder cancer growth in model systems. We h...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487994/ https://www.ncbi.nlm.nih.gov/pubmed/22898175 http://dx.doi.org/10.1186/1471-2490-12-21 |