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Correlation between single nucleotide polymorphisms in CYP4F2 and warfarin dosing in chinese valve replacement patients
BACKGROUND: Individuals with implanted mechanical valve prostheses require lifelong anticoagulation therapy with warfarin. The narrow therapeutic index of warfarin makes it difficult to dose and maintain proper anticoagulation. A number of single nucleotide polymorphisms (SNPs) affecting vitamin K o...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487995/ https://www.ncbi.nlm.nih.gov/pubmed/23013706 http://dx.doi.org/10.1186/1749-8090-7-97 |