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A yeast expression system for functional and pharmacological studies of the malaria parasite Ca(2+)/H(+) antiporter

BACKGROUND: Calcium (Ca(2+)) signalling is fundamental for host cell invasion, motility, in vivo synchronicity and sexual differentiation of the malaria parasite. Consequently, cytoplasmic free Ca(2+) is tightly regulated through the co-ordinated action of primary and secondary Ca(2+) transporters....

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Detalles Bibliográficos
Autores principales: Salcedo-Sora, J Enrique, Ward, Steve A, Biagini, Giancarlo A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488005/
https://www.ncbi.nlm.nih.gov/pubmed/22853777
http://dx.doi.org/10.1186/1475-2875-11-254