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Genetic diversity of expressed Plasmodium falciparum var genes from Tanzanian children with severe malaria

BACKGROUND: Severe malaria has been attributed to the expression of a restricted subset of the var multi-gene family, which encodes for Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1). PfEMP1 mediates cytoadherence and sequestration of infected erythrocytes into the post-capillary venu...

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Detalles Bibliográficos
Autores principales: Mugasa, Joseph, Qi, Weihong, Rusch, Sebastian, Rottmann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488018/
https://www.ncbi.nlm.nih.gov/pubmed/22799500
http://dx.doi.org/10.1186/1475-2875-11-230