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The bacterial ribonuclease P holoenzyme requires specific, conserved residues for efficient catalysis and substrate positioning
RNase P is an RNA-based enzyme primarily responsible for 5′-end pre-tRNA processing. A structure of the bacterial RNase P holoenzyme in complex with tRNA(Phe) revealed the structural basis for substrate recognition, identified the active site location, and showed how the protein component increases...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488217/ https://www.ncbi.nlm.nih.gov/pubmed/22904083 http://dx.doi.org/10.1093/nar/gks744 |