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The slicing activity of miRNA-specific Argonautes is essential for the miRNA pathway in C. elegans
Among the set of Argonautes proteins encoded by metazoan genomes, some have conserved amino acids important for catalytic or slicing activity. The functional significance of these residues in microRNA (miRNA)-specific Argonautes in animals is still unclear since miRNAs do not induce site-specific cl...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488219/ https://www.ncbi.nlm.nih.gov/pubmed/22904066 http://dx.doi.org/10.1093/nar/gks748 |