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A global sampling approach to designing and reengineering RNA secondary structures

The development of algorithms for designing artificial RNA sequences that fold into specific secondary structures has many potential biomedical and synthetic biology applications. To date, this problem remains computationally difficult, and current strategies to address it resort to heuristics and s...

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Detalles Bibliográficos
Autores principales: Levin, Alex, Lis, Mieszko, Ponty, Yann, O’Donnell, Charles W., Devadas, Srinivas, Berger, Bonnie, Waldispühl, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488226/
https://www.ncbi.nlm.nih.gov/pubmed/22941632
http://dx.doi.org/10.1093/nar/gks768