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Bacterial topoisomerase I and topoisomerase III relax supercoiled DNA via distinct pathways

Escherichia coli topoisomerases I and III (Topo I and Topo III) relax negatively supercoiled DNA and also catenate/decatenate DNA molecules containing single-stranded DNA regions. Although these enzymes share the same mechanism of action and have similar structures, they participate in different cel...

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Detalles Bibliográficos
Autores principales: Terekhova, Ksenia, Gunn, Kathryn H., Marko, John F., Mondragón, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488232/
https://www.ncbi.nlm.nih.gov/pubmed/22923519
http://dx.doi.org/10.1093/nar/gks780