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In vivo identification of essential nucleotides in tRNA(Leu) to its functions by using a constructed yeast tRNA(Leu) knockout strain
The fidelity of protein biosynthesis requires the aminoacylation of tRNA with its cognate amino acid catalyzed by aminoacyl-tRNA synthetase with high levels of accuracy and efficiency. Crucial bases in tRNA(Leu) to aminoacylation or editing functions of leucyl-tRNA synthetase have been extensively s...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488233/ https://www.ncbi.nlm.nih.gov/pubmed/22917587 http://dx.doi.org/10.1093/nar/gks783 |