Structural basis for the substrate recognition and catalysis of peptidyl-tRNA hydrolase

Peptidyl-tRNA hydrolase (Pth) cleaves the ester bond between the peptide and the tRNA of peptidyl-tRNA molecules, which are produced by aborted translation, to recycle tRNA for further rounds of protein synthesis. Pth is ubiquitous in nature, and its enzymatic activity is essential for bacterial via...

Descripción completa

Detalles Bibliográficos
Autores principales: Ito, Kosuke, Murakami, Ryo, Mochizuki, Masahiro, Qi, Hao, Shimizu, Yoshihiro, Miura, Kin-ichiro, Ueda, Takuya, Uchiumi, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488237/
https://www.ncbi.nlm.nih.gov/pubmed/22923517
http://dx.doi.org/10.1093/nar/gks790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488237/
https://www.ncbi.nlm.nih.gov/pubmed/22923517
http://dx.doi.org/10.1093/nar/gks790

Ejemplares similares