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Misacylation of tRNA with methionine in Saccharomyces cerevisiae

Accurate transfer RNA (tRNA) aminoacylation by aminoacyl-tRNA synthetases controls translational fidelity. Although tRNA synthetases are generally highly accurate, recent results show that the methionyl-tRNA synthetase (MetRS) is an exception. MetRS readily misacylates non-methionyl tRNAs at frequen...

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Detalles Bibliográficos
Autores principales: Wiltrout, Elizabeth, Goodenbour, Jeffrey M., Fréchin, Mathieu, Pan, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488245/
https://www.ncbi.nlm.nih.gov/pubmed/22941646
http://dx.doi.org/10.1093/nar/gks805