DNA repair endonuclease ERCC1–XPF as a novel therapeutic target to overcome chemoresistance in cancer therapy

The ERCC1–XPF complex is a structure-specific endonuclease essential for the repair of DNA damage by the nucleotide excision repair pathway. It is also involved in other key cellular processes, including DNA interstrand crosslink (ICL) repair and DNA double-strand break (DSB) repair. New evidence ha...

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Detalles Bibliográficos
Autores principales: McNeil, Ewan M., Melton, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Survey and Summary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488251/
https://www.ncbi.nlm.nih.gov/pubmed/22941649
http://dx.doi.org/10.1093/nar/gks818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488251/
https://www.ncbi.nlm.nih.gov/pubmed/22941649
http://dx.doi.org/10.1093/nar/gks818

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