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The THO complex cooperates with the nuclear RNA surveillance machinery to control small nucleolar RNA expression

THO is a multi-protein complex that promotes coupling between transcription and mRNA processing. In contrast to its role in mRNA biogenesis, we show here that the fission yeast THO complex negatively controls the expression of non-coding small nucleolar (sno) RNAs. Accordingly, the deletion of genes...

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Detalles Bibliográficos
Autores principales: Larochelle, Marc, Lemay, Jean-François, Bachand, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488260/
https://www.ncbi.nlm.nih.gov/pubmed/22965128
http://dx.doi.org/10.1093/nar/gks838