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Rationale and design of a double-blind, placebo-controlled, randomized trial to evaluate the safety and efficacy of nimodipine in preventing cognitive impairment in ischemic cerebrovascular events (NICE)

BACKGROUND: Stroke is the second most common cause of mortality and the leading cause of neurological disability, cognitive impairment and dementia worldwide. Nimodipine is a dihydropyridinic calcium antagonist with a role in neuroprotection, making it a promising therapy for vascular cognitive impa...

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Detalles Bibliográficos
Autores principales: Wang, Penglian, Wang, Yongjun, Feng, Tao, Zhao, Xingquan, Zhou, Yong, Wang, Yilong, Shi, Weixiong, Ju, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488311/
https://www.ncbi.nlm.nih.gov/pubmed/22950711
http://dx.doi.org/10.1186/1471-2377-12-88