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Sorafenib modulates the radio sensitivity of hepatocellular carcinoma cells in vitro in a schedule-dependent manner

BACKGROUND: Hepatocellular carcinoma (HCC) has a high incidence and mortality. Radiotherapy and sorafenib have proven effective for HCC. Here, we investigated whether sorafenib modulated the response of HCC cells to irradiation in vitro, effect of timing of sorafenib, and the underlying mechanisms....

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Detalles Bibliográficos
Autores principales: Li, Qiaoqiao, Hu, Yonghong, Xi, Mian, He, Liru, Zhao, Lei, Liu, Mengzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488336/
https://www.ncbi.nlm.nih.gov/pubmed/23088517
http://dx.doi.org/10.1186/1471-2407-12-485