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Reversible Oxidation of Myometrial Voltage-Gated Potassium Channels with Hydrogen Peroxide

The uteri, spontaneously active or Ca(2+) (6 mM) induced, were allowed to equilibrate, and to inhibit voltage-gated potassium (K (V)) channels 1 mM 4-amino pyridine (4-AP) was applied for 15 min before adding H(2)O(2) .  H(2)O(2) was added cumulatively: 2 μM, 20 μM, 200 μM, 400 μM, and 3 mM. Average...

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Detalles Bibliográficos
Autores principales: Appiah, Isabella, Nikolic-Kokic, Aleksandra, Orescanin-Dusic, Zorana, Radojicic, Ratko, Milovanovic, Slobodan, Spasic, Mihajlo, Blagojevic, Dusko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488416/
https://www.ncbi.nlm.nih.gov/pubmed/23150748
http://dx.doi.org/10.1155/2012/105820