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Delayed apoptosis by neutrophils from COPD patients is associated with altered bak, bcl-xl, and mcl-1 mRNA expression

BACKGROUND: Delayed neutrophil apoptosis may be an important factor in the persistent inflammation associated with chronic obstructive pulmonary disease (COPD). Bcl-2 family proteins are important regulators of neutrophil apoptosis. We determined the mRNA levels of pro-apoptotic Bak and anti-aptotot...

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Detalles Bibliográficos
Autores principales: Zhang, Jisong, He, Jian, Xia, Jingwen, Chen, Zhen, Chen, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488503/
https://www.ncbi.nlm.nih.gov/pubmed/22686245
http://dx.doi.org/10.1186/1746-1596-7-65