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Delayed apoptosis by neutrophils from COPD patients is associated with altered bak, bcl-xl, and mcl-1 mRNA expression
BACKGROUND: Delayed neutrophil apoptosis may be an important factor in the persistent inflammation associated with chronic obstructive pulmonary disease (COPD). Bcl-2 family proteins are important regulators of neutrophil apoptosis. We determined the mRNA levels of pro-apoptotic Bak and anti-aptotot...
Autores principales: | Zhang, Jisong, He, Jian, Xia, Jingwen, Chen, Zhen, Chen, Xiaodong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488503/ https://www.ncbi.nlm.nih.gov/pubmed/22686245 http://dx.doi.org/10.1186/1746-1596-7-65 |
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