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TGFβ signalling plays an important role in IL4-induced alternative activation of microglia

BACKGROUND: Microglia are the resident immune cells of the central nervous system and are accepted to be involved in a variety of neurodegenerative diseases. Several studies have demonstrated that microglia, like peripheral macrophages, exhibit two entirely different functional activation states, re...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaolai, Spittau, Björn, Krieglstein, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488564/
https://www.ncbi.nlm.nih.gov/pubmed/22947253
http://dx.doi.org/10.1186/1742-2094-9-210