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Ephrin-A1 inhibits NSCLC tumor growth via induction of Cdx-2 a tumor suppressor gene

BACKGROUND: Tumor formation is a complex process which involves constitutive activation of oncogenes and suppression of tumor suppressor genes. Receptor EphA2 and its ligand ephrin-A1 form an important cell communication system with its functional role in cell-cell interaction and tumor growth. Loss...

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Detalles Bibliográficos
Autores principales: Sukka-Ganesh, Bhagyalaxmi, Mohammed, Kamal A, Kaye, Frederic, Goldberg, Eugene P, Nasreen, Najmunnisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488573/
https://www.ncbi.nlm.nih.gov/pubmed/22824143
http://dx.doi.org/10.1186/1471-2407-12-309