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Characterization and function of the human macrophage dopaminergic system: implications for CNS disease and drug abuse

BACKGROUND: Perivascular macrophages and microglia are critical to CNS function. Drugs of abuse increase extracellular dopamine in the CNS, exposing these cells to elevated levels of dopamine. In rodent macrophages and human T-cells, dopamine was shown to modulate cellular functions through activati...

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Detalles Bibliográficos
Autores principales: Gaskill, Peter J, Carvallo, Loreto, Eugenin, Eliseo A, Berman, Joan W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488577/
https://www.ncbi.nlm.nih.gov/pubmed/22901451
http://dx.doi.org/10.1186/1742-2094-9-203