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Level of phosphohistone H3 among various types of human cancers

OBJECTIVES: Anti-phosphorylated histone H3 (pHH3) antibodies specifically detect the core protein histone H3 only when phosphorylated at serine 10 (Ser10) or serine 28 (Ser28). Measurement of pHH3 levels can be used for quantifying mitosis and the effectiveness of mitotic inhibitors in early drug de...

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Detalles Bibliográficos
Autores principales: Sun, Amy, Zhou, Wei, Lunceford, Jared, Strack, Peter, Dauffenbach, Lisa M, Kerfoot, Christopher A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488750/
https://www.ncbi.nlm.nih.gov/pubmed/23065444
http://dx.doi.org/10.1136/bmjopen-2012-001071