ABCB1 4036A>G and 1236C>T Polymorphisms Affect Plasma Efavirenz Levels in South African HIV/AIDS Patients

The ABCB1 gene encodes P-glycoprotein, an ATP-dependent drug efflux pump, which is responsible for drug transport across extra- and intra-cellular membranes. The variability in the expression of ABCB1 may contribute to variable plasma efavirenz concentration which results in variability in the level...

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Detalles Bibliográficos
Autores principales: Swart, Marelize, Ren, Yuan, Smith, Peter, Dandara, Collet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488761/
https://www.ncbi.nlm.nih.gov/pubmed/23133441
http://dx.doi.org/10.3389/fgene.2012.00236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488761/
https://www.ncbi.nlm.nih.gov/pubmed/23133441
http://dx.doi.org/10.3389/fgene.2012.00236

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