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Molecular interaction analysis of cigarette smoke carcinogens NNK and NNAL with enzymes involved in DNA repair pathways: An in silico approach

DNA damage occurs almost all the times in cells, but is repaired also continuously. Occurrence of all these mutations and their accumulation in one cell which finally becomes tumorigenic/carcinogenic appears possible if the DNA repair mechanism is hampered. We hypothesize that alterations in DNA rep...

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Detalles Bibliográficos
Autores principales: Jamal, Qazi Mohd Sajid, Lohani, Mohtashim, Siddiqui, Mohd Haris, Haneef, Mohd, Gupta, Shailendra Kumar, Wadhwa, Gulshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488840/
https://www.ncbi.nlm.nih.gov/pubmed/23139587
http://dx.doi.org/10.6026/97320630008795