PIK3CA exon 20 mutations are associated with poor prognosis in breast cancer patients

OBJECTIVES: The phosphatidylinositol 3-kinase/AKT axis is an important cell-signaling pathway that mediates cell proliferation and survival, two biological processes that regulate malignant cell growth. The phosphatidylinositol 3-kinase CA gene encodes the p110α subunit of the phosphatidylinositol 3...

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Detalles Bibliográficos
Autores principales: Mangone, Flavia R., Bobrovnitchaia, Irina G., Salaorni, Sibeli, Manuli, Erika, Nagai, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2012
Materias:
Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488987/
https://www.ncbi.nlm.nih.gov/pubmed/23184205
http://dx.doi.org/10.6061/clinics/2012(11)11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488987/
https://www.ncbi.nlm.nih.gov/pubmed/23184205
http://dx.doi.org/10.6061/clinics/2012(11)11

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