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PIK3CA exon 20 mutations are associated with poor prognosis in breast cancer patients

OBJECTIVES: The phosphatidylinositol 3-kinase/AKT axis is an important cell-signaling pathway that mediates cell proliferation and survival, two biological processes that regulate malignant cell growth. The phosphatidylinositol 3-kinase CA gene encodes the p110α subunit of the phosphatidylinositol 3...

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Detalles Bibliográficos
Autores principales:	Mangone, Flavia R., Bobrovnitchaia, Irina G., Salaorni, Sibeli, Manuli, Erika, Nagai, Maria A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2012
Materias:	Clinical Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488987/ https://www.ncbi.nlm.nih.gov/pubmed/23184205 http://dx.doi.org/10.6061/clinics/2012(11)11

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