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A statistical model-building perspective to identification of MS/MS spectra with PeptideProphet

PeptideProphet is a post-processing algorithm designed to evaluate the confidence in identifications of MS/MS spectra returned by a database search. In this manuscript we describe the "what and how" of PeptideProphet in a manner aimed at statisticians and life scientists who would like to...

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Detalles Bibliográficos
Autores principales: Ma, Kelvin, Vitek, Olga, Nesvizhskii, Alexey I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489532/
https://www.ncbi.nlm.nih.gov/pubmed/23176103
http://dx.doi.org/10.1186/1471-2105-13-S16-S1