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Pharmacokinetics and modeling of immune cell trafficking: quantifying differential influences of target tissues versus lymphocytes in SJL and lipopolysaccharide-treated mice

BACKGROUND: Immune cell trafficking into the CNS and other tissues plays important roles in health and disease. Rapid quantitative methods are not available that could be used to study many of the dynamic aspects of immune cell-tissue interactions. METHODS: We used pharmacokinetics and modeling to q...

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Detalles Bibliográficos
Autores principales: Banks, William A, Niehoff, Michael L, Ponzio, Nicholas M, Erickson, Michelle A, Zalcman, Steven S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489553/
https://www.ncbi.nlm.nih.gov/pubmed/23034075
http://dx.doi.org/10.1186/1742-2094-9-231