Transcriptional response of BALB/c mouse thyroids following in vivo astatine-211 exposure reveals distinct gene expression profiles

BACKGROUND: Astatine-211 ((211)At) is an alpha particle emitting halogen with almost optimal linear energy transfer for creating DNA double-strand breaks and is thus proposed for radionuclide therapy when bound to tumor-seeking agents. Unbound (211)At accumulates in the thyroid gland, and the concep...

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Detalles Bibliográficos
Autores principales: Rudqvist, Nils, Parris, Toshima Z, Schüler, Emil, Helou, Khalil, Forssell-Aronsson, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489558/
https://www.ncbi.nlm.nih.gov/pubmed/22697397
http://dx.doi.org/10.1186/2191-219X-2-32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489558/
https://www.ncbi.nlm.nih.gov/pubmed/22697397
http://dx.doi.org/10.1186/2191-219X-2-32

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