Reducing ligation bias of small RNAs in libraries for next generation sequencing

BACKGROUND: The use of nucleic acid-modifying enzymes has driven the rapid advancement in molecular biology. Understanding their function is important for modifying or improving their activity. However, functional analysis usually relies upon low-throughput experiments. Here we present a method for...

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Detalles Bibliográficos
Autores principales: Sorefan, Karim, Pais, Helio, Hall, Adam E, Kozomara, Ana, Griffiths-Jones, Sam, Moulton, Vincent, Dalmay, Tamas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489589/
https://www.ncbi.nlm.nih.gov/pubmed/22647250
http://dx.doi.org/10.1186/1758-907X-3-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489589/
https://www.ncbi.nlm.nih.gov/pubmed/22647250
http://dx.doi.org/10.1186/1758-907X-3-4

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