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Reducing ligation bias of small RNAs in libraries for next generation sequencing
BACKGROUND: The use of nucleic acid-modifying enzymes has driven the rapid advancement in molecular biology. Understanding their function is important for modifying or improving their activity. However, functional analysis usually relies upon low-throughput experiments. Here we present a method for...
Autores principales: | Sorefan, Karim, Pais, Helio, Hall, Adam E, Kozomara, Ana, Griffiths-Jones, Sam, Moulton, Vincent, Dalmay, Tamas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489589/ https://www.ncbi.nlm.nih.gov/pubmed/22647250 http://dx.doi.org/10.1186/1758-907X-3-4 |
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